WebPubChem BioAssay contains small-molecule and RNAi screening data along with associated annotation information from contributing organizations. WebJul 7, 2015 · Content identification. Publications containing relevant data were selected in two ways. Firstly a set of documents was selected using the ChEMBL-likeness text …
ChEMBL Database - European Bioinformatics Institute
WebThe 'browse entity' sections are used through all the interface to show subsets of data in ChEMBL. For example, to see the activities related to the compound SILIBININ you can go to this page and see a 'browse … WebJul 5, 2024 · In this work, we demonstrate that in vivo assay data in ChEMBL are, despite their largely unstructured format, a valuable resource for direct use in data-driven drug discovery and optimization. We show that the descriptions of screening assays can be effectively and efficiently mined and classified using a combination of modern text … chp heme onc
ChEMBL: towards direct deposition of bioassay data
WebThis information is then added to the ChEMBL database. You can then search it for specific target by name or sequence or do substructure or similarity searches to find data on specific chemotypes. If an article has data on measurements made in cell-based assays, in vivo pharmacology assays or pharmacokinetic studies for compounds we will also ... WebDec 2, 2011 · The mission of PubChem is to deliver free and easy access to all deposited data, and to provide intuitive data analysis tools. The PubChem BioAssay database currently contains 500 000 descriptions of assay protocols, covering 5000 protein targets, 30 000 gene targets and providing over 130 million bioactivity outcomes. WebDec 5, 2024 · Allow easier access to in vivo assays that describe animal disease models or phenotypic endpoints (Hunter et al.). Complement the chemical probe information available in the Open Targets Platform with the probes available in ChEMBL. For example, BRD4, bromodomain containing 4 has multiple chemical probes with bioactivity data in … chp helmond