WebApr 19, 2014 · Abstract. Background : Clopidogrel bisulfate is a class of drugs or antiplatelet platelet antiagregasi solubility practically insoluble in water and are also included in the second class of ... WebSep 1, 2024 · Plavix (clopidogrel tablets) is a thienopyridine class inhibitor of P2Y 12 ADP platelet receptors. Chemically it is methyl (+)-(S)-α-(2-chlorophenyl)-6,7-dihydrothieno[3,2-c] ... Clopidogrel bisulfate is a white to off-white powder. It is practically insoluble in water at neutral pH but freely soluble at pH 1. It also dissolves freely in ...
Clopidogrel (Oral Route) Description and Brand Names - Mayo Clinic
WebDosage/Direction for Use. Adult & elderly 75 mg as a single daily dose. Non-ST-segment elevation acute coronary syndrome (unstable angina or non-Q-wave MI) Initially, single 300 or 600 mg loading dose. Continue treatment at 75 mg once daily (w/ ASA 75-325 mg once daily). Patient <75 yr May consider 600 mg loading dose when percutaneous coronary ... WebApo-Clopidogrel: Clopidogrel belongs to the class of medications called platelet aggregation inhibitors or antiplatelets. Clopidogrel is used to help prevent heart attacks, strokes, and other circulation problems for people who have atherosclerosis (narrowed blood vessels caused by "hardening of the arteries") and have already experienced at least … george brown application deadline
MATERIAL SAFETY DATA SHEET - Pfizer
WebMay 5, 2024 · Clopidogrel bisulfate can increase the systemic exposure to drugs that are primarily cleared by CYP2C8, thereby needing dose adjustment and appropriate monitoring. ... Clopidogrel bisulfate is a thienopyridine class inhibitor of P2Y 12 ADP platelet receptors. Chemically it is methyl (+)-( S)-α-(2-chlorophenyl)-6,7-dihydrothieno [3,2 … WebClopidogrel is a prodrug that is metabolised mainly by CYP2C19 into active form. CYP2C19 gene variants are known to be associated with increased or decreased response to clopidogrel. The prevalence of CYP2C19 poor metabolisers has been estimated in 2% of Caucasians, 4% of African Americans, and 14% of Chinese. WebNov 28, 2024 · Clopidogrel tablets, USP are a thienopyridine class inhibitor of P2Y 12 ADP platelet receptors. Chemically it is methyl (+)-( S)-α-(2-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5( 4H)acetate sulfate (1:1). The empirical formula of clopidogrel bisulfate is C 16 H 16 ClNO 2 S•H 2 SO 4 and its molecular weight is 419.9. The structural ... george brown bim