WebNov 8, 2013 · Cardizem is a prescription medication used to control chest pain and treats high blood pressure. Cardizem belongs to a group of drugs called calcium channel blockers. These work by relaxing the blood vessels so the heart does not need to work as hard. … WebSep 15, 2024 · The mechanism of bisphosphonates-induced AF is unclear, but these drugs release inflammatory cytokines and shorten atrial action potential duration and effective refractory period. Mechanisms of atrial …
Proarrhythmia - an overview ScienceDirect Topics
WebFeb 19, 2024 · The antiarrhythmic medications have typically been categorized according to the Vaughan-Williams (VW) classification system. The system classifies the medications according to the primary mechanism of action (although several agents retain properties … WebProarrhythmia is reported between 5.9% and 15.8% depending on agent, clinical setting and definition of proarrhythmia, and now considered ubiquitous with all antiarrhythmic drugs. Proarrhythmia has been defined as an increase in frequency of ventricular … porters strategy mix
Drugs for Conversion of Atrial Fibrillation AAFP
WebOct 23, 1997 · Proarrhythmia Associated With The Use Of d,l-Sotalol. Besides its action potential prolonging action, sotalol, which is a racemic mixture of d- and l-isomers (both of which have equal potency for prolonging the action potential duration), is also a … WebJan 15, 2024 · Class III antiarrhythmics. This class prolongs and slows down the outward movement of potassium during phase 3 of action potential. These drugs act directly on the heart muscles to prolong repolarization and refractory period. All of these drugs are proarrhythmic and have the possibility of inducing arrhythmias. WebOct 23, 1997 · The nature of the proarrhythmic reactions induced by antiarrhythmic drugs is linked to the electrophysiologic effects of these agents. Torsades de pointes is the classic form of proarrhythmia observed during therapy with any drug that prolongs repolarization, for example, the class III agents. Its precise electrophysiologic mechanism … porters three generic competitive strategies