Webarchitecture defining the AdoMet and phosphobase binding sites. Functional characterization of 27 site-directed mutants identifies critical active site residues and suggests that Tyr-19 and His-132 form a catalytic dyad. Kinetic analysis, isothermal titration calorimetry, and protein crystallography of the Y19F WebPhosphoBase is a database of experimentally verified phosphorylation sites. Version 1.0 contains 156 entries and 398 experimentally determined phosphorylation sites.
PhosphoSitePlus
WebPhospholipase C yields a 1,2-diacylglycerol and the phosphobase moiety, while phospholipase D yields 1,2-diacylglycerol 3-phosphate (phosphatidic acid) and the base. Type B phospholipases can remove fatty acids from both sn− 1 and sn− 2 positions, but these enzymes are quite rare. Phospholipases are important in the digestion of dietary ... WebAug 6, 2010 · The current release of PhosphoBase (October 1998, version 2.0) comprises 414 phosphoprotein entries covering 1052 phosphorylatable serine, threonine and … robert young mass general hospital
PhosphoBase, a database of phosphorylation sites: release 2.0.
WebA resource on protein phosphatases, a key class of regulatory proteins. Includes genomic and evolutionary analyses (phosphatomes), classification, disease associationa and an extensive database of protein phosphatase genes. WebDec 29, 2024 · The phosphobase methylation pathway, in which phosphoethanolamine (pEA) 2 is converted to phosphocholine (pCho) in three successive methylation steps, is … WebTEXT Description CEPT1 is a dual-specificity enzyme that catalyzes ethanolaminephosphotransferase ( EC 2.7.8.1) and cholinephosphotransferase ( EC 2.7.8.2) reactions for the synthesis of phosphatidylethanolamine and phosphatidylcholine, respectively ( Henneberry and McMaster, 1999 ). Cloning and Expression robert young matlock