WebOct 6, 2024 · Cisplatin, 5-FU, and paclitaxel which are common chemotherapeutic drugs for cervical cancer were tested. We performed proliferation and apoptosis analysis of cervical cells after treatment with morphine or chemotherapeutic drugs alone or … WebMar 20, 2024 · Cisplatin (CDDP) is a platinum-based antitumor drug [ 1 ]. Its widespread use in the treatment of breast cancer, ovarian cancer, and other cancers has greatly improved the survival rate of patients [ 1 – 4 ]. However, this process is often accompanied by serious side effects, including nephrotoxicity and ototoxicity [ 5 ].
Cisplatin (NSC 119875) ≥99%(HPLC) Selleck DNA/RNA合成 阻 …
WebMar 1, 2024 · Cisplatin-related ototoxicity is a critical side effect of chemotherapy and can lead to irreversible hearing loss. This study aimed to assess the potential effect of the DNA methyltransferase (DNMT) inhibitor RG108 on cisplatin-induced ototoxicity. ... RG108 and LY294002 were purchased from Selleck Chemicals (Houston, TX, USA) and initially ... WebJul 1, 2024 · Olaparib, cisplatin and paclitaxel were purchased from Selleck Chemicals and prepared in 10 mM stocks. The initial concentrations of olaparib, cisplatin and paclitaxel were 160 µM, 800 µM and 160 nM, respectively, for the half maximal inhibitory concentration (IC 50) determinations. Agents were diluted to 7 concentrations with 4-fold serial ... slow iron 45
Morphine stimulates cervical cancer cells and alleviates …
WebMar 23, 2024 · Combinations of Cisplatin with talazoparib and niraparib effectively reduced the survival of BLCA cells, while veliparib was not effective even at high concentrations. In vivo, the combinations of cisplatin with niraparib, rucaparib, or talazoparib reduced BLCA xenograft growth significantly. Conclusions WebJun 9, 2024 · Overlaying single cell readouts of cell cycle and apoptosis onto a multidimensional analysis of pulsed cisplatin signalling dynamics reveals targetable mechanisms of platinum resistance in lung adenocarcinoma. ... Selleck Chem: S1009: Chemical compound, drug: MK-2206 2HCl: Selleck Chem: S1078: Chemical compound, … WebCisplatin已被证实可有效作用于多种动物肿瘤模型,抑制肿瘤生长,包括头颈部肿瘤移植瘤,宫颈鳞状细胞癌移植瘤,睾丸癌移植瘤,卵巢癌移植瘤,乳腺癌移植瘤,结肠癌移植 … slow iron dose